About 30 results found for searched term "Enzymes" (0.113 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7540 | Pancreatin | Cell Culture |
| pancrelipase, Pancreatic enzymes | ||
| Pancreatic enzymes also known as pancrelipase and pancreatin, are commercial mixtures of amylase, lipase, and protease. They are used to treat malabsorption syndrome due to pancreatic problems. | ||
| M2349 | (R)-Nepicastat hydrochloride | HCV Protease |
| RS-25560-198 HCl | ||
| (R)-Nepicastat hydrochloride, the R-enantiomer of Nepicastat hydrochloride, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors. | ||
| M2297 | Devimistat (CPI-613) | Dehydrogenase |
| Devimistat | ||
| Devimistat (CPI-613) inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase. | ||
| M2418 | AZD1981 | GPR/FFAR |
| AZD1981 is a potent, selective CRTh2 (DP2) receptor antagonist with IC50 of 4 nM, showing >1000-fold selectivity over more than 340 other enzymes and receptors, including DP1. | ||
| M3992 | Avibactam | Antibiotic |
| Avibactam is a non-β-lactam β-lactamase inhibitor with a spectrum of activity that includes β-lactamase enzymes of classes A, C, and selected D examples. | ||
| M4896 | Nicotinamide | Sirtuin |
| Vitamin B3; Nicotinic acid amide; Niacinamide | ||
| Nicotinamide is an active component of coenzymes NAD and NADP, and also act as an inhibitor of sirtuins. Nicotinamide plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. | ||
| M4945 | Enasidenib | Isocitrate Dehydrogenase (IDH) |
| AG-221 | ||
| Enasidenib is an oral, potent, reversible, selective inhibitor of the IDH2 mutant enzymes, with IC50s of 100 and 400 nM against IDH2R140Q and IDH2R172K, respectively. | ||
| M5136 | GSK-LSD1 dihydrochloride | Histone demethylase |
| GSK-LSD1 2HCl | ||
| GSK-LSD1 2HCl is an irreversible, and selective LSD1 inhibitor with IC50 of 16 nM, > 1000 fold selective over other closely related FAD utilizing enzymes (i.e. LSD2, MAO-A, MAO-B). | ||
| M5834 | Oltipraz | HIF |
| RP 35972; NSC 347901 | ||
| Oltipraz is a potent Nrf2 activator and a potent inducer of Phase II detoxification enzymes, most notably glutathione-S-transferase (GST). | ||
| M6112 | Thiamine chloride | Vitamin |
| Vitamin B1 | ||
| Thiamine chloride —the biologically active form of vitamin B1—is vital for all cellular life because it is a co-factor for several essential enzymes. | ||
| M6136 | Epacadostat | IDO |
| INCB024360 | ||
| Epacadostat (INCB024360) is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM and displays high selectivity over other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO). | ||
| M10542 | Alternariol | Topoisomerase |
| Alternariol is a mycotoxin produced by Alternaria species. Alternariol inhibits the catalytic activity of topoisomerase I and topoisomerase II enzymes. | ||
| M7541 | TUG-770 | GPR/FFAR |
| Tug-770 is a potent, selective, orally active GPR40/FFA1 agonist with an EC50 of 6 nM against human FFA1. Tug-770 has higher selectivity to FFA1 than FFA2, FFA3, FFA4, PPARγ, other receptors, transporters and enzymes. | ||
| M8208 | 4-Phenylbutyryl hydroxamic acid | Others |
| 4-Phenylbutyryl hydroxamic acid is a cell permeable HDAC inhibitor which is about 100 times more potent than parent carboxylic acid among nine HDAC enzymes. | ||
| M8377 | UCM710 | Others |
| UCM710 is a dual inhibitor of fatty acid amide hydrolase (FAAH) and α/β hydrolase domain 6 (ABHD6) the enzymes that hydrolyze endocannabinoids. | ||
| M8465 | WWL113 | Others |
| WWL113 is an inhibitor of mouse Carboxylesterase 3 (Ces3) and human CES1 (orthologue of mCes3), serine hydrolases involved in lipolysis in addition to their activities as liver detoxification enzymes. | ||
| M8466 | WWL229 | Others |
| WWL229 is a highly selective inhibitor of mouse Carboxylesterase 3 (Ces3) and human CES1 (orthologue of mCes3), serine hydrolases involved in lipolysis in addition to their activities as liver detoxification enzymes. | ||
| M8473 | RA-9 | Others |
| RA-9 is a cell permeable and potent inhibitor of the ubiquitin-proteasome system (UPS) that targets deubiquitinating enzymes (DUB) without affecting 20S proteasome catalytic-core activity. | ||
| M8773 | Liarozole dihydrochloride | Others |
| Liarozole (R 75251, R75,251) is an orally active benzimidazole-based retinoic acid (RA) metabolism blocking agent (RAMBA) that targets multiple P450 enzymes, including aromatase (CYP19), 17-hydroxylase/17,20-lyas |
||
| M8783 | Lys05 | Autophagy |
| Lys01 trihydrochloride | ||
| Lys05 (Lys01 trihydrochloride) is a dimeric chloroquine (CQ) that deacidifies the lysosome and causes impairment of lysosomal enzymes, exhibiting more than 10-fold higher autophagy inhibitory potency than hydroxychloroquine (HCQ) and CQ (LC3II/LC3I ratio = 15. | ||
| M9034 | Mitapivat (AG-348) | Pyruvate Kinase |
| PKR-IN-1; PKM2 activator 1020; Pyrukynd； AG-348 | ||
| Mitapivat (AG-348) is the first-in-class, oral effective pyruvate kinase small molecule allosteric activator. Mitapivat (AG-348) is active against wild-type and various mutated PKR enzymes, and promotes healthy red blood cell generation by activating mutated PKR to increase ATP levels. | ||
| M9049 | MPTP HCl | Dopamine Receptor |
| MPTP hydrochloride; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Hydrochloride | ||
| MPTP is dehydrogenated in nigrostriatal cells to generate MPP+, which in turn inhibits mitochondrial complex enzymes and contributes to cell death. It can be used to construct animal models of Parkinson's disease. | ||
| M9076 | NADPH tetrasodium salt | Others |
| β-NADPH | ||
| NADPH tetrasodium salt is a cofactor, used to donate electrons and a hydrogens to reactions catalyzed by some enzymes. | ||
| M9735 | ND-646 | Others |
| ND646 | ||
| ND-646 is an allosteric inhibitor of the ACC enzymes ACC1 and ACC2 with IC50 values of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively. | ||
| M9932 | Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine | Others |
| TBTA | ||
| Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine (TBTA) is a ligand that acts as a biochemical tool for the tagging of proteins and enzymes. | ||
| M10024 | Temperature Sensitive Ice Box | Cold Storage |
| AbMole Temperature Sensitive Ice Box uses Thermochromic Materials to indcate the temperature change, it is suitable for short-term transportation and storage of temperature sensitive samples (such as enzymes, antibodies, PCR samples, etc.). | ||
| M10534 | Tucidinostat (Chidamide) HCl | HDAC |
| Chidamide; HBI-8000; CS-055 HCl | ||
| Tucidinostat (HBI-8000; Chidamide; CS-055) HCl is a benzamide type inhibitor of histone deacetylase (HDAC) isoenzymes 1, 2, 3 and 10 with IC50 values of 95, 160, 67, 78 nM for HDAC1, 2, 3, 10 respectively. | ||
| M10748 | SW-100 | HDAC |
| SW-100 is a potent inhibitor of histone deacetylase 6 (HDAC6),IC50 The value is 2.3 nM, which is at least 1000 times more selective for HDAC6 than other HDAC enzymes. Sw-100 significantly improves the ability to cross the blood-brain barrier. | ||
| M10951 | CMP-5 | PRMTs |
| CMP-5 is a potent and selective PRMT5 inhibitor that is inactive against PRMT1, PRMT4, and PRMT7 enzymes. CMP-5 selectively blocks S2Me-H4R3 by inhibiting PRMT5 methyltransferase activity during histone preparation. CMP-5 blocks EBV-driven B lymphocyte transformation but has no effect on normal B cells. | ||
| M11031 | 2-Chloroacetamide | Antibiotic |
| 2-Chloroacetamide is a preservative that is a herbicide for drylands and paddy fields. 2-Chloroacetamide is a fungicide in agriculture, glue, paints and coatings. 2-Chloroacetamide inhibits ultra-long chain fatty acid extending enzymes. | ||
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.
